Research across a wide range of specialties
At the NIHR St George’s Clinical Research Facility, we support clinical research across a broad range of medical and surgical specialties.
Our teams work with hospital consultants, clinical departments, academic partners, industry sponsors and patients to deliver studies that improve understanding, treatment and care. Our research includes observational studies, interventional trials, academic studies, commercial studies, device evaluations and early-phase clinical trials.
By supporting research across many areas of medicine, we help create more opportunities for patients and volunteers to take part in studies that may shape the future of healthcare.
Gastroenterology and Endoscopy
Our Gastroenterology and Endoscopy Research Team supports studies focused on diseases of the gastrointestinal tract and endoscopy-related care.
Research areas include:
- Ulcerative colitis
- Crohn’s disease
- Gastroparesis
- Eosinophilic oesophagitis
- Bile acid diarrhoea
- Interventional endoscopy
- Bowel cancer risk prevention studies
These studies may explore new treatments, improve existing care, support earlier diagnosis or help us better understand risk factors and patient outcomes.
Oncology
Our Solid Tumour Research Team delivers clinical trials aimed at improving treatments and outcomes for people affected by cancer.
Research areas include:
- Lung cancer
- Breast cancer
- Gastrointestinal cancers, including colorectal and upper GI cancer
- Urological cancers, including prostate and bladder cancer
- Rare urological cancers, such as penile cancer
- Melanoma
- Renal cancer
Our oncology studies may include drug trials, immunotherapy, targeted therapy, chemotherapy, combination treatments, biomarker studies and quality-of-life research.
Endocrine and Diabetes
We support research across common and rare endocrine conditions, including:
- Type 1 diabetes
- Type 2 diabetes
- Obesity
- Rare endocrine disorders
These studies aim to improve treatment options, monitoring, long-term outcomes and quality of life for people living with endocrine and metabolic conditions.
Respiratory Medicine
Our respiratory research supports patients with chronic and complex lung conditions.
Research areas include:
- Pulmonary fibrosis
- Interstitial lung disease
- Chronic obstructive pulmonary disease
- Bronchiectasis
- Home non-invasive ventilation for motor neurone disease
These studies help improve understanding, treatment and management of respiratory conditions.
Infectious Diseases
We conduct research in both seasonal and emerging infections.
Research areas include:
- Influenza
- Community-acquired pneumonia
- Arboviral infections
Our infectious diseases research helps improve prevention, diagnosis, treatment and care for patients affected by infection.
ENT: Ear, Nose and Throat
Our ENT portfolio includes device-based and outcomes research in hearing and related care.
Research areas include:
- Cochlear implants
- Hearing aids
These studies help evaluate treatments, devices and patient outcomes to improve care and quality of life.
Vascular Surgery
We support surgical, interventional and device evaluation studies in vascular care.
Research areas include:
- Abdominal aortic aneurysm
- Peripheral arterial disease
- Lower limb amputations
- Angioplasty
- Post-market medical device evaluation
Our vascular research helps assess treatment approaches, devices and long-term outcomes for patients with vascular conditions.
Cardiac Surgery
Our cardiac research spans surgical care, recovery and rehabilitation.
Research areas include:
- Atrial fibrillation
- Coronary artery bypass graft surgery
- Cardiac rehabilitation
These studies aim to improve outcomes before, during and after cardiac surgery.
General Surgery
We support studies across selected areas of general surgery, including:
- Cholecystectomy, also known as gallbladder surgery
- Anal fistula
Our general surgery research helps improve treatment pathways, surgical outcomes and patient recovery.
Dermatology and Genetics
We have specialist experience in rare and complex dermatology and genetic conditions.
Research areas include:
- Lymphatic malformations
- PIK3CA-related overgrowth spectrum
These studies support better understanding, diagnosis and treatment of rare and complex conditions.
A broad and evolving research portfolio
Our research portfolio continues to grow as new studies open and new partnerships develop. Across all specialties, our aim is to deliver safe, inclusive and high-quality research that improves care for patients now and in the future.
Patients may be considered for research if a suitable study is available and eligibility criteria are met. Taking part is always voluntary, and our teams are here to provide clear information and support at every stage.